Animal Husbandry and Feed Science

2019, v.11(01) 35-38

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Correlation Analysis of Drug Resistance and Resistant Genotypes of Pathogenic Klebsiella peneumoniae from Racoon Dog to Fluoroquinolones
Correlation Analysis of Drug Resistance and Resistant Genotypes of Pathogenic Klebsiella peneumoniae from Racoon Dog to Fluoroquinolones

Zhao Xiaocui;Liu Zhiqiang;Luo Junfeng;Yao Weiping;Feng Ling;Wu Tonglei;Zhang Zhiqiang;Bai Xue;Fu Yanfang;Gao Qingshan;Jia Qinghui;Shi Qiumei;

摘要(Abstract):

[Objective] The paper was to analyze the correlation between drug resistance and resistant genotypes of pathogenic Klebsiella peneumoniae from racoon dog to fluoroquinolones. [Method] The drug resistance and resistant genes of 24 strains of pathogenic K. peneumoniae from racoon dog to fluoroquinolones were detected by K-B drug susceptibility paper and PCR. [Result] Multiple drug-resistant strains were dominant among 24 strains of pathogenic K. peneumoniae, and the drug resistance to levofloxacin, enrofloxacin, ciprofloxacin and norfloxacin was 70.8%-79.2%; the strains resistant to 4, 3 and 2 antibiotics were 58.3%, 29.2% and 8.3%, respectively. The detection rates of drug-resistant genes TEM, gyrB, parC,parE, gyrA and SHV were 75%-100%, and the number of strains carrying 9, 8, 7, 6, 4 and 3 drug-resistant genes was 4.2%-41.7%. Comparison of drug-resistant genes and drug resistance showed that the coincidence rates of levofloxacin, enrofloxacin, ciprofloxacin and norfloxacin were 78.9%-100%. [Conclusion] There were certain correlation between drug resistance and resistant genotypes of 24 strains of pathogenic Klebsiella peneumo-niae to fluoroquinolones.

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基金项目(Foundation): Supported by Project of Hebei Department of Science and Technology(18246629G);; Project of Shijiazhuang Science and Technology Bureau(171500953A);; Project of Hebei Department of Education(ZD2017234)

作者(Author): Zhao Xiaocui;Liu Zhiqiang;Luo Junfeng;Yao Weiping;Feng Ling;Wu Tonglei;Zhang Zhiqiang;Bai Xue;Fu Yanfang;Gao Qingshan;Jia Qinghui;Shi Qiumei;

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